| 别名 | CDCA5; Cell division cycle associated protein 5; Cell division cycle-associated protein 5; p35; Sororin; |
| 基因名称 | CDCA5 |
| 蛋白名称 | CDCA5 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 113130; |
| Human Swissprot No. | Q96FF9 |
| Mouse Gene ID | 67849; |
| Mouse Swissprot No. | Q9CPY3; |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed): 35 kDa |
| 预测分子量 | MW(Calculated): 28 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Regulator of sister chromatid cohesion in mitosis stabilizing cohesin complex association with chromatin. May antagonize the action of WAPAL which stimulates cohesin dissociation from chromatin. Cohesion ensures that chromosome partitioning is accurate in both meiotic and mitotic cells and plays an important role in DNA repair. Required for efficient DNA double-stranded break repair. |
| 细胞定位 | Chromosome, Cytoplasm, Nucleus. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Chromosome, Cytoplasm, Nucleus. |
| 组织表达 | Testis, Bone marrow, Intestinal epithelium, Breast carcinoma, Lung cancer, Colorectal carcinoma |
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