| 别名 | HSPA4; APG-2; APG2; Heat shock 70kD protein 4; Hsp70RY; HSPH2; Hsp70; HS24/P52; Heat shock 70kDa protein 4; Heat shock protein 110 kDa; |
| 基因名称 | HSPA4 |
| 蛋白名称 | HSPA4 |
| 推荐应用 | |
| 反应物种 | Human(WB);Human Mouse Rat(IHC) |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 5062; |
| Human Swissprot No. | P34932 |
| Mouse Gene ID | 224105; |
| Mouse Swissprot No. | Q8CIN4 |
| Rat Gene ID | 29432; |
| Rat Swissprot No. | Q64303; |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed): 110 kDa |
| 预测分子量 | MW(Calculated): 94 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The heat shock protein HSPA4 (Apg-2, HSP70RY) is a member of the heat-shock protein 110 (Hsp 110) subfamily of Hsp70 heat-shock proteins. Apg-2 has chaperone ability similiar to Hsp110, and it plays a role under non-stress conditions. Apg-2 interacts with TJP1/ZO-1 and functions as a regulator of ZO-1-ZONAB signaling in epithelial cells in response to cellular stress. |
| 细胞定位 | [Serine/threonine-protein kinase PAK 2]: Cytoplasm. MYO18A mediates the cellular distribution of the PAK2-ARHGEF7-GIT1 complex to the inner surface of the cell membrane.; [PAK-2p34]: Nucleus. Cytoplasm , perinuclear region. Membrane; Lipid-anchor. Interaction with ARHGAP10 probably changes PAK-2p34 location to cytoplasmic perinuclear region. Myristoylation changes PAK-2p34 location to the membrane. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | [Serine/threonine-protein kinase PAK 2]: Cytoplasm. MYO18A mediates the cellular distribution of the PAK2-ARHGEF7-GIT1 complex to the inner surface of the cell membrane.; [PAK-2p34]: Nucleus. Cytoplasm , perinuclear region. Membrane; Lipid-anchor. Interaction with ARHGAP10 probably changes PAK-2p34 location to cytoplasmic perinuclear region. Myristoylation changes PAK-2p34 location to the membrane. |
| 组织表达 | Ubiquitous expression |
周一至周日 8:00-18:00
