| 别名 | Lymphocyte-specific protein 1; Protein pp52; 52 kDa phosphoprotein; Lymphocyte-specific antigen WP34; 47 kDa actin-binding protein; |
| 基因名称 | LSP1 |
| 蛋白名称 | LSP1 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 4046; |
| Human Swissprot No. | P33241 |
| Mouse Gene ID | 16985 |
| Mouse Swissprot No. | P19973 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:1000~1:2000 |
| 参考分子量 | MW(Observed): 52 kDa |
| 预测分子量 | MW(Calculated): 37 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | LSP1 is a 52 kDa leukocyte-specific protein expressed in B cells, T cells, macrophages and neutrophils. The protein binds F-actin through its C-terminal actin-binding repeat and regulates cytoskeletal-related cellular movement such as polarization, chemotaxis and locomotion. LSP1 is a phospho-protein and has been identified as a major substrate of MAP kinase and PKC in lymphocytes and neutrophils. |
| 细胞定位 | Cell membrane; Peripheral membrane protein; Cytoplasmic side. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell membrane; Peripheral membrane protein; Cytoplasmic side. |
| 组织表达 | Spleen, Lymph node, Bone marrow, Lymphoma, Leukemia, Multiple myeloma |
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