| 别名 | ACAC; ACACA; ACACB; ACC; ACC-alpha; ACC1; ACC2; ACCA; ACCB; Acetyl-CoA carboxylase 1; Biotin carboxylase; |
| 基因名称 | Acetyl-CoA Carboxylase |
| 蛋白名称 | Acetyl-CoA Carboxylase |
| 推荐应用 | |
| 反应物种 | Human Mouse |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 31; 32; |
| Human Swissprot No. | Q13085;O00763 |
| Mouse Gene ID | 107476 |
| Mouse Swissprot No. | Q5SWU9 |
| Rat Gene ID | 60581 |
| Rat Swissprot No. | P11497 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:1000~1:2000 |
| 参考分子量 | MW(Observed): 265 kDa |
| 预测分子量 | MW(Calculated): 265kDa/276kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | ACC1 a subunit of acetyl-CoA carboxylase (ACC), a multifunctional enzyme system. Catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. Acetyl-CoA carboxylase (ACC) catalyzes the pivotal step of the fatty acid synthesis pathway. The 265 kDa ACCα (ACC1) is the predominant isoform found in liver, adipocytes, and mammary gland, while the 280 kDa ACCβ (ACC2) is the major isoform in skeletal muscle and heart. |
| 细胞定位 | actin cytoskeleton, cytosol, fibrillar center, mitochondrion. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | actin cytoskeleton, cytosol, fibrillar center, mitochondrion. |
| 组织表达 | Liver, Adipose tissue, Muscle, Hepatocellular carcinoma, Adipocytic tumor, Muscle sarcoma |
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