| 别名 | GPRC1E; GRM5; Metabotropic glutamate receptor 5 precursor; MGLUR5; MGR5; |
| 基因名称 | GRM5 |
| 蛋白名称 | GRM5 |
| 推荐应用 | |
| 反应物种 | Mouse Rat(WB);Human Mouse Rat(IHC) |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 2915 |
| Human Swissprot No. | P41594 |
| Mouse Gene ID | 108071 |
| Mouse Swissprot No. | Q3UVX5 |
| Rat Gene ID | 24418 |
| Rat Swissprot No. | P31424 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed): 150 kDa |
| 预测分子量 | MW(Calculated): 132 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | G-protein coupled receptor for glutamate. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling activates a phosphatidylinositol-calcium second messenger system and generates a calcium-activated chloride current. Plays an important role in the regulation of synaptic plasticity and the modulation of the neural network activity. |
| 细胞定位 | Cell membrane, Multi-pass membrane protein. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell membrane, Multi-pass membrane protein. |
| 组织表达 | Brain, Spinal cord, Glioma, Neuroblastoma, Medulloblastoma, Alzheimer's disease brain |
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