| 别名 | NADPH oxidase 4; Kidney oxidase-1; KOX-1; KOX1; Kidney superoxide-producing NADPH oxidase; Renal NAD(P)H-oxidase; NOX4; RENOX; |
| 基因名称 | NOX4 |
| 蛋白名称 | NOX4 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 50507 |
| Human Swissprot No. | Q9NPH5 |
| Mouse Gene ID | 50490 |
| Mouse Swissprot No. | Q9JHI8 |
| Rat Gene ID | 85431 |
| Rat Swissprot No. | Q924V1 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:1000~1:2000 |
| 参考分子量 | MW(Observed): 67 kDa |
| 预测分子量 | MW(Calculated): 67 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The superoxide-generating NADPH oxidase includes a membrane-bound flavocytochrome containing two subunits, gp91-phox and p22-phox, and the cytosolic proteins p47-phox and p67-phox. During activation of the NADPH oxidase, p47-phox and p67-phox migrate to the plasma membrane where they associate with the flavocytochrome, cytochrome b558, to form the active enzyme complex. |
| 细胞定位 | Cell membrane, Nucleus, Endoplasmic reticulum membrane. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell membrane, Nucleus, Endoplasmic reticulum membrane. |
| 组织表达 | Kidney, Lung, Liver, Renal cell carcinoma, Lung cancer, Hepatocellular carcinoma, Breast carcinoma |