| 别名 | Dipeptidyl peptidase 4; ADABP; Adenosine deaminase complexing protein 2; ADCP-2; Dipeptidyl peptidase IV; DPP IV; T-cell activation antigen CD26; TP103; CD26; DPP4; ADCP2; DPP 4; DPP IV; |
| 基因名称 | CD26 |
| 蛋白名称 | CD26 |
| 推荐应用 | |
| 反应物种 | Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 1803; |
| Human Swissprot No. | P27487 |
| Mouse Gene ID | 13482 |
| Mouse Swissprot No. | P28843 |
| Rat Gene ID | 25253 |
| Rat Swissprot No. | P14740 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed): 110 kDa |
| 预测分子量 | MW(Calculated): 88 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 细胞定位 | [Dipeptidyl peptidase 4 soluble form]: Secreted . Detected in the serum and the seminal fluid. .; Cell membrane ; Single-pass type II membrane protein. Apical cell membrane ; Single-pass type II membrane protein. Cell projection , invadopodium membrane ; Single-pass type II membrane protein. Cell projection , lamellipodium membrane ; Single-pass type II membrane protein. Cell junction . Membrane raft . Translocated to the apical membrane through the concerted action of N- and O-Glycans and its association with lipid microdomains containing cholesterol and sphingolipids (PubMed:11773049) . Redistributed to membrane rafts in T-cell in an interleukin-12-dependent activation (PubMed:12676959) . Its interaction with CAV1 is necessary for its translocation to membrane rafts (PubMed:17287217) . Colocalized with PTPRC in membrane rafts (PubMed:12676959) . Colocalized with FAP in invadopodia and lamellipodia of migratory activated endothelial cells in collagenous matrix. Colocalized with FAP on endothelial cells of capillary-like microvessels but not large vessels within invasive breast ductal carcinoma (PubMed:16651416) . Colocalized with ADA at the cell junction in lymphocyte-epithelial cell adhesion (PubMed:11772392) . Colocalized with IGF2R in internalized cytoplasmic vesicles adjacent to the cell surface (PubMed:10900005) . |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | [Dipeptidyl peptidase 4 soluble form]: Secreted . Detected in the serum and the seminal fluid. .; Cell membrane ; Single-pass type II membrane protein. Apical cell membrane ; Single-pass type II membrane protein. Cell projection , invadopodium membrane ; Single-pass type II membrane protein. Cell projection , lamellipodium membrane ; Single-pass type II membrane protein. Cell junction . Membrane raft . Translocated to the apical membrane through the concerted action of N- and O-Glycans and its association with lipid microdomains containing cholesterol and sphingolipids (PubMed:11773049) . Redistributed to membrane rafts in T-cell in an interleukin-12-dependent activation (PubMed:12676959) . Its interaction with CAV1 is necessary for its translocation to membrane rafts (PubMed:17287217) . Colocalized with PTPRC in membrane rafts (PubMed:12676959) . Colocalized with FAP in invadopodia and lamellipodia of migratory activated endothelial cells in collagenous matrix. Colocalized with FAP on endothelial cells of capillary-like microvessels but not large vessels within invasive breast ductal carcinoma (PubMed:16651416) . Colocalized with ADA at the cell junction in lymphocyte-epithelial cell adhesion (PubMed:11772392) . Colocalized with IGF2R in internalized cytoplasmic vesicles adjacent to the cell surface (PubMed:10900005) . |
| 组织表达 | Kidney, Small intestine, Liver, Renal cell carcinoma, Colorectal carcinoma, Hepatocellular carcinoma |
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