| 别名 | CDC23; ANAPC8; APC8; Cell division cycle 23; CUT23; Cyclosome subunit 8; |
| 基因名称 | Cdc23/APC8 |
| 蛋白名称 | Cdc23/APC8 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 8697 |
| Human Swissprot No. | Q9UJX2 |
| Mouse Gene ID | 52563 |
| Mouse Swissprot No. | Q8BGZ4 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):64kD |
| 预测分子量 | MW(Calculated):69kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Anaphase-promoting complex subunit 8 (APC8, CDC23) is a component of the tetratricopeptide repeat (TPR) APC/C sub-complex that also includes APC3 (CDC27) and APC6 (CDC16). APC8 protein associates with APC3 and APC6 to facilitate recruitment of the APC/C coactivation subunits CDC20 and Cdh1/FZR1. Research studies suggest that APC8 protein is overexpressed in papillary thyroid cancer and acts as an important regulator of cell cycle progression and cell growth. |
| 细胞定位 | Cytosol. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytosol. |
| 组织表达 | Widely expressed (Testis, Thymus, Bone marrow) |
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