| 别名 | Dual specificity mitogen-activated protein kinase kinase 1; MAP kinase kinase 1; MAPKK 1; MKK1; ERK activator kinase 1; MAPK/ERK kinase 1; MEK 1; MAP2K1; MEK-1; PRKMK1; |
| 基因名称 | Phospho-MEK1 (S298) |
| 蛋白名称 | Phospho-MEK1 (S298) |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 5604 |
| Human Swissprot No. | Q02750 |
| Mouse Gene ID | 26395 |
| Mouse Swissprot No. | P31938 |
| Rat Gene ID | 170851 |
| Rat Swissprot No. | Q01986 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:1000~1:2000 |
| 参考分子量 | MW(Observed):45kD |
| 预测分子量 | MW(Calculated):43kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Activation of MEK1 and MEK2 occurs through phosphorylation of two serine residues at positions 217 and 221, located in the activation loop of subdomain VIII, by Raf-like molecules. Catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. Activates ERK1 and ERK2 MAP kinases. |
| 细胞定位 | Cytoplasm, Nucleus, Membrane. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Phospho |
| 细胞定位 | Cytoplasm, Nucleus, Membrane. |
| 组织表达 | Widely expressed (Brain, Liver, Lung) |
周一至周日 8:00-18:00
