| 别名 | ACACA kinase; Acetyl-CoA carboxylase kinase; AMPK subunit alpha-2; AMPK2; AMPKalpha2; HMGCR kinase; Hydroxymethylglutaryl-CoA reductase kinase; PRKAA; PRKAA2; |
| 基因名称 | Phospho-AMPK alpha 2 (S345) |
| 蛋白名称 | Phospho-AMPK alpha 2 (S345) |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 5563 |
| Human Swissprot No. | P54646 |
| Mouse Swissprot No. | Q8BRK8 |
| Rat Swissprot No. | Q09137 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:1000~1:2000 |
| 参考分子量 | MW(Observed):64kD |
| 预测分子量 | MW(Calculated):62kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | AMP-activated protein kinase (AMPK) is highly conserved from yeast to plants and animals and plays a key role in the regulation of energy homeostasis. AMPK is a heterotrimeric complex composed of a catalytic α subunit and regulatory β and γ subunits, each of which is encoded by two or three distinct genes (α1, 2; β1, 2; γ1, 2, 3). The kinase is activated by an elevated AMP/ATP ratio due to cellular and environmental stress, such as heat shock, hypoxia, and ischemia. |
| 细胞定位 | Cytoplasm, Nucleus. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Phospho |
| 细胞定位 | Cytoplasm, Nucleus. |
| 组织表达 | Widely expressed (Liver, Kidney, Lung) |
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