| 别名 | SIR2L6; SIR2-like protein 6; NAD-dependent protein deacetylase sirtuin-6; Regulatory protein SIR2 homolog 6; Sirtuin 6; |
| 基因名称 | SIRT6 |
| 蛋白名称 | SIRT6 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 51548 |
| Human Swissprot No. | Q8N6T7 |
| Mouse Swissprot No. | P59941 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:1000~1:2000 |
| 参考分子量 | MW(Observed):39kD |
| 预测分子量 | MW(Calculated):39 kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The Silent Information Regulator (Sir2) family of genes is a highly conserved group of genes that encode nicotinamide adenine dinucleotide (NAD)-dependent protein deacetylases, also known as class III histone deacetylases. SirT6, a mammalian homolog of Sir2, is a nuclear, chromatin-associated protein that promotes the normal maintenance of genome integrity mediated by the base excision repair (BER) pathway. |
| 细胞定位 | Nucleus, Chromosome, telomere, Endoplasmic reticulum. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Nucleus, Chromosome, telomere, Endoplasmic reticulum. |
| 组织表达 | Widely expressed (Liver, Kidney, Lung) |
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