| 别名 | Zinc finger protein GLI1; Glioma-associated oncogene; Oncogene GLI; Zfp5; GLI family zinc finger 1;GLI; |
| 基因名称 | Gli1 |
| 蛋白名称 | Gli1 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 2735 |
| Human Swissprot No. | P08151 |
| Mouse Gene ID | 14632 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:1000 |
| 参考分子量 | MW(Observed): 160 kDa |
| 预测分子量 | MW(Calculated): 118 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | GLI belongs to the Kruppel family of zinc finger proteins that includes three mammalian GLI proteins: GLI1, GLI2, and GLI3. Acts as a transcriptional activator. May regulate the transcription of specific genes during normal development. May play a role in craniofacial development and digital development, as well as development of the central nervous system and gastrointestinal tract. Mediates SHH signaling and thus cell proliferation and differentiation. |
| 细胞定位 | Cytoplasm, Nucleus. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Nucleus. |
| 组织表达 | Brain, Lung, Skin, Glioma, Basal cell carcinoma, Lung cancer, Breast cancer. |
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