| 别名 | SK; DKK-1; Dickkopf-related protein 1; Dickkopf-1; hDkk-1; Dickkopf homolog 1; |
| 基因名称 | DKK1 |
| 蛋白名称 | DKK1 |
| 推荐应用 | |
| 反应物种 | Human Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 22943; |
| Human Swissprot No. | O94907 |
| Mouse Gene ID | 13380; |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:1000~1:2000 |
| 参考分子量 | MW(Observed): 38 kDa |
| 预测分子量 | MW(Calculated): 29 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | DKK1: dickkopf homolog 1 (Xenopus laevis), also known as SK. Entrez Protein NP_036374. DKK1 is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. |
| 细胞定位 | Secreted. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Secreted. |
| 组织表达 | Bone, Cartilage, Lung, Osteosarcoma, Lung cancer, Breast cancer, Colon cancer. |
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