| 别名 | RALBP1; RIP1; RLIP1; RLIP76; |
| 基因名称 | RALBP1 |
| 蛋白名称 | RALBP1 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 10928; |
| Human Swissprot No. | Q15311 |
| Mouse Gene ID | 19765 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:5000~1:10000 |
| 参考分子量 | MW(Observed): 95 kDa |
| 预测分子量 | MW(Calculated): 76 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | RalBP1 interacts with RalA and the endocytosis protein REPS2 (POB1) through its carboxy-terminal Ral binding domain. RalBP1 has an intrinsic GTPase activating function and interacts with Cdc42 through its centrally located Rho-GAP domain. A protein complex containing RalBP1/POB1/RalA regulates endocytosis of membrane receptors. RalBP1 also functions as a non-ABC transporter that catalyzes the ATP-dependent transport of numerous xenobiotics, including glutathione conjugates and some chemotherapeutic agents. |
| 细胞定位 | Membrane, Peripheral membrane protein. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Membrane, Peripheral membrane protein. |
| 组织表达 | Widely expressed (Liver, Kidney, Lung) |