| 别名 | SB1.8/DXS423E protein; SM1A; SMC1A; SMC1L1; SMC1alpha protein; Sb1.8; |
| 基因名称 | Phospho-SMC1 (S957) |
| 蛋白名称 | Phospho-SMC1 (S957) |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 8243 |
| Human Swissprot No. | Q14683 |
| Mouse Gene ID | 24061 |
| Mouse Swissprot No. | Q9CU62 |
| Rat Gene ID | 63996 |
| Rat Swissprot No. | Q9Z1M9 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):160kD |
| 预测分子量 | MW(Calculated):143kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Structural maintenance of chromosomes 1 (SMC1) protein is a chromosomal protein member of the cohesin complex that enables sister chromatid cohesion and plays a role in DNA repair . ATM/NBS1-dependent phosphorylation of SMC1 occurs at Ser957 and Ser966 in response to ionizing radiation (IR) as part of the intra-S-phase DNA damage checkpoint. SMC1 phosphorylation is ATM-independent in cells subjected to other forms of DNA damage, including UV light and hydroxyurea treatment. |
| 细胞定位 | Nucleus, Chromosome, centromere. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Phospho |
| 细胞定位 | Nucleus, Chromosome, centromere. |
| 组织表达 | Widely expressed (Testis, Thymus, Bone marrow) |
周一至周日 8:00-18:00
