| 别名 | REPA2; RF-A; RP-A; RPA2; RPA32; replication factor-A protein 2; replication protein A 32 kDa subunit; replication protein A2; |
| 基因名称 | Phospho-RPA2 (T21) |
| 蛋白名称 | Phospho-RPA2 (T21) |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 6118 |
| Human Swissprot No. | P15927 |
| Mouse Swissprot No. | Q62193 |
| Rat Gene ID | 59102 |
| Rat Swissprot No. | Q63528 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:5000~1:10000 |
| 参考分子量 | MW(Observed):32kD |
| 预测分子量 | MW(Calculated):29kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. In the cellular response to DNA damage, the RPA complex controls DNA repair and DNA damage checkpoint activation. |
| 细胞定位 | Nucleus. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Phospho |
| 细胞定位 | Nucleus. |
| 组织表达 | Widely expressed (Testis, Thymus, Bone marrow) |