| 别名 | 65 kDa phosphoprotein; CSBP; TUNP; HNRNPK; HNRPK; DC-stretch binding protein; hnRNP-K; |
| 基因名称 | hnRNP K |
| 蛋白名称 | hnRNP K |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 3190 |
| Human Swissprot No. | P61978 |
| Mouse Gene ID | 15387 |
| Mouse Swissprot No. | P61979 |
| Rat Gene ID | 117282 |
| Rat Swissprot No. | P61980 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:5000~1:10000 |
| 参考分子量 | MW(Observed):60kD |
| 预测分子量 | MW(Calculated):51kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Facilitate pre-mRNA processing and transport of mRNA from the nucleus to cytoplasm. hnRNP K contains three unique structural motifs termed KH domains that bind poly(C) DNA and RNA sequences. Intricate architecture enables hnRNP K to facilitate mRNA biosynthesis, transcriptional regulation, and signal transduction. Research studies have shown that cytoplasmic hnRNP K expression is increased in oral squamous cell carcinoma and pancreatic cancer, and may be a potential prognostic factor. |
| 细胞定位 | Nucleoplasm, Cytoplasm, podosome |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Nucleoplasm, Cytoplasm, podosome |
| 组织表达 | Widely expressed (Liver, Kidney, Lung) |
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