| 别名 | CJD; GSS; PrP; PRNP; ASCR; KURU; PRIP; PrPc; CD230; AltPrP; Prion protein; PrP27-30; PrP33-35C; |
| 基因名称 | Prion Protein |
| 蛋白名称 | Prion Protein |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 5621 |
| Human Swissprot No. | P04156 |
| Mouse Swissprot No. | P04925 |
| Rat Swissprot No. | P13852 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:1000~1:2000 |
| 参考分子量 | MW(Observed):28kD |
| 预测分子量 | MW(Calculated):28kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The PRNP gene encodes the major prion protein (PrP, CD230), a widely-expressed glycoprotein expressed at high levels in the central nervous system. While the typical cellular function of PrP is not well defined, it is a putative antioxidant and a metal-binding protein that may be involved in signal transduction. |
| 细胞定位 | Golgi apparatus, Cell membrane. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Golgi apparatus, Cell membrane. |
| 组织表达 | Brain, Spinal cord, Retina, Glioma, Neuroblastoma, Lung cancer. |