| 别名 | RSK; HU-1; RSK1; MAPKAPK1A; RPS6KA1; |
| 基因名称 | Phospho-RSK1(S380) |
| 蛋白名称 | Phospho-RSK1(S380) |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 6195 |
| Human Swissprot No. | Q15418 |
| Mouse Swissprot No. | P18653 |
| Rat Gene ID | 81771 |
| Rat Swissprot No. | Q63531 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):90kD |
| 预测分子量 | MW(Calculated):83kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Rsk1 is a member of a family of 90kDa ribosomal protein S6 kinases, which includes Rsk1, Rsk2 and Rsk3. These are broadly expressed serine / threonine protein kinases activated in response to mitogenic stimuli, including extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. Active Rsks appear to play a major role in transcriptional regulation by translocating to the nucleus and phosphorylating c-Fos and CREB. |
| 细胞定位 | Nucleus, Cytoplasm. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Phospho |
| 细胞定位 | Nucleus, Cytoplasm. |
| 组织表达 | Widely expressed (Brain, Liver, Lung) |
周一至周日 8:00-18:00
