| 别名 | PP2A alpha; PP2A beta; Replication protein C; PPP2CA; PPP2CB; |
| 基因名称 | PP2A alpha + beta |
| 蛋白名称 | PP2A alpha + beta |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 5515;5516 |
| Human Swissprot No. | P62714;P67775 |
| Mouse Gene ID | 19052;19053 |
| Mouse Swissprot No. | P63330;P62715 |
| Rat Gene ID | 24672;24673 |
| Rat Swissprot No. | P63331;P62716 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):36kD |
| 预测分子量 | MW(Calculated):36kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Protein phosphatase type 2A (PP2A) is an essential protein serine/threonine phosphatase that is conserved in all eukaryotes. PP2A is a key enzyme within various signal transduction pathways as it regulates fundamental cellular activities such as DNA replication, transcription, translation, metabolism, cell cycle progression, cell division, apoptosis and development. The core enzyme consists of catalytic C and regulatory A (or PR65) subunits, with each subunit represented by α and β isoforms. |
| 细胞定位 | Cytoplasm, Nucleus, Chromosome, centromere, cytoskeleton, spindle pole. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Nucleus, Chromosome, centromere, cytoskeleton, spindle pole. |
| 组织表达 | Widely expressed (Brain, Liver, Lung) |
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