| 别名 | CSDD2; FLJ16517; LIN28B; Protein lin-28 homolog B; |
| 基因名称 | Lin28B |
| 蛋白名称 | Lin28B |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 389421 |
| Human Swissprot No. | Q6ZN17 |
| Mouse Swissprot No. | Q45KJ6 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):30kD |
| 预测分子量 | MW(Calculated):30kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | It has recently been shown that upregulation of LIN28A and LIN28B in primary human tumors and human cancer cell lines is correlated with downregulation of let-7 miRNAs. LIN28 genes are reported to be involved in primordial germ cell development and germ cell malignancy. In addition, allelic variation in LIN28B is associated with regulating the timing of puberty in humans. |
| 细胞定位 | Nucleus, nucleolus, Cytoplasm. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Nucleus, nucleolus, Cytoplasm. |
| 组织表达 | Testis, Placenta, Embryonic tissue, Testicular cancer, Ovarian cancer, Lung cancer, Breast cancer. |
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