| 别名 | Caspase-2; Caspase 2; Caspase2; CASP-2; Neural precursor cell expressed developmentally down-regulated protein 2; NEDD-2; Protease ICH-1; CASP2; ICH1; NEDD2 |
| 基因名称 | Caspase-2 |
| 蛋白名称 | Caspase-2 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 835 |
| Human Swissprot No. | P42575 |
| Mouse Swissprot No. | P29594 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~2000 |
| 参考分子量 | MW(Observed):48,30,12kD |
| 预测分子量 | MW(Calculated):51kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Caspase-2 (Nedd2, ICH-1) is an aspartate-specific cysteine protease that is activated in response to various apoptotic stimuli. Caspase-2 is unique among the caspases in that it has features of both upstream caspases (long prodomain) and downstream caspases (DEXD substrate specificity). Caspase-2 is highly expressed in the brain during development and is expressed at low levels in adult tissue. |
| 细胞定位 | Cytoplasm, Nucleus, Membrane. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Nucleus, Membrane. |
| 组织表达 | Widely expressed (Spleen, Liver, Lung) |
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