| 别名 | FAK; FADK; FAK1; FRNK; pp125FAK; PTK2; |
| 基因名称 | FAK |
| 蛋白名称 | FAK |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 5747 |
| Human Swissprot No. | Q05397 |
| Mouse Gene ID | 14083 |
| Mouse Swissprot No. | P34152 |
| Rat Gene ID | 25614 |
| Rat Swissprot No. | O35346 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):119kD |
| 预测分子量 | MW(Calculated):119kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. |
| 细胞定位 | Cytoplasm, Nucleus, Cell membrane, Cell junction. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Nucleus, Cell membrane, Cell junction. |
| 组织表达 | Widely expressed (Brain, Liver, Lung) |
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