| 别名 | HH19; MKP3; PYST1; DUSP6; DUSP6a; Dual specificity phosphatase 6; |
| 基因名称 | DUSP6 |
| 蛋白名称 | DUSP6 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 1848 |
| Human Swissprot No. | Q16828 |
| Mouse Gene ID | 67603 |
| Mouse Swissprot No. | Q9DBB1 |
| Rat Gene ID | 116663 |
| Rat Swissprot No. | Q64346 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):42kD |
| 预测分子量 | MW(Calculated):42kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | MAP kinases are inactivated by dual-specificity protein phosphatases (DUSP) that differ in their substrate specificity, tissue distribution, inducibility by extracellular stimuli and cellular localization. DUSPs, also known as MAPK phosphatases (MKP), specifically dephosphorylate both threonine and tyrosine residues in MAPK P-loops and have been shown to play important roles in regulating the function of the MAPK family. At least 13 members of the family (DUSP1-10, DUSp14, DUSP16, and DUSP22) display unique substrate specificities for various MAP kinases. |
| 细胞定位 | Cytoplasm. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm. |
| 组织表达 | Widely expressed (Brain, Liver, Lung) |
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