| 别名 | Gp80-LNGFR; NGF receptor; p75 ICD; CD271; NGFR; TNFRSF16; |
| 基因名称 | NGFR |
| 蛋白名称 | NGFR |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 4804 |
| Human Swissprot No. | P08138 |
| Mouse Swissprot No. | Q9Z0W1 |
| Rat Gene ID | 24596 |
| Rat Swissprot No. | P07174 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:10000~1:20000 |
| 参考分子量 | MW(Observed):75kD |
| 预测分子量 | MW(Calculated):75kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | NGFR Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Homodimer; disulfide-linked. Interacts with p75NTR- associated cell death executor. Interacts with TRAF2, TRAF4, TRAF6, PTPN13 and RANBP9. Interacts through TRAF6 with SQSTM1 which bridges NGFR to NTRK1. Interacts with BEX1 and NGFRAP1/BEX3. Interacts with KIDINS220 and NTRK1. |
| 细胞定位 | Membrane |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Membrane |
| 组织表达 | Brain, Spinal cord, Skin, Glioma, Neuroblastoma, Melanoma, Lung cancer. |
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