| 别名 | CLG3; matrix metalloproteinase 13 (collagenase 3); MMP13; |
| 基因名称 | MMP13 |
| 蛋白名称 | MMP13 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 4322 |
| Human Swissprot No. | P45452 |
| Mouse Gene ID | 17386 |
| Mouse Swissprot No. | P33435 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):54kD |
| 预测分子量 | MW(Calculated):54kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Defects in MMP13 are the cause of spondyloepimetaphyseal dysplasia Missouri type (SEMD-MO) [MIM:602111]. A bone disease characterized by moderate to severe metaphyseal changes, mild epiphyseal involvement, rhizomelic shortening of the lower limbs with bowing of the femora and/or tibiae, coxa vara, genu varum and pear-shaped vertebrae in childhood. Epimetaphyseal changes improve with age. |
| 细胞定位 | Secreted, extracellular space, extracellular matrix. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Secreted, extracellular space, extracellular matrix. |
| 组织表达 | Bone, Cartilage, Synovium, Osteosarcoma, Chondrosarcoma, Breast cancer, Colon cancer. |
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