| 别名 | F11R;CD321;JAM;JAM-1;JAM-A;JAM1;JAMA;JCAM;KAT;PAM-1;Junction adhesion molecule 1; |
| 基因名称 | JAM1 |
| 蛋白名称 | JAM1 |
| 推荐应用 | |
| 反应物种 | Human Mouse |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 50848 |
| Human Swissprot No. | Q9Y624 |
| Mouse Gene ID | 16456 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed): 33 kDa |
| 预测分子量 | MW(Calculated): 32 kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Seems to plays a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier. Involved in platelet activation. In case of orthoreovirus infection, serves as receptor for the virus. |
| 细胞定位 | Cell junction, Cell membrane, Single-pass type I membrane protein, tight junction. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell junction, Cell membrane, Single-pass type I membrane protein, tight junction. |
| 组织表达 | Widely expressed (Epithelium, Endothelium, Liver) |
周一至周日 8:00-18:00
