| 别名 | CHEK2; CHK2; Cds1; Chk2; EC 2.7.11.1; RAD53; kinase Chk2; |
| 基因名称 | Chk2 |
| 蛋白名称 | Chk2 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 11200 |
| Human Swissprot No. | O96017 |
| Mouse Gene ID | 50883 |
| Mouse Swissprot No. | Q9Z265 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:10000~1:20000 |
| 参考分子量 | MW(Observed):62kD |
| 预测分子量 | MW(Calculated):61kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | These are known to be preferred sites for phosphorylation by ATM/ATR kinases. After DNA damage by ionizing radiation (IR), UV irradiation, or hydroxyurea treatment, Thr68 and other sites in this region become phosphorylated by ATM/ATR. The SQ/TQ cluster domain, therefore, seems to have a regulatory function. |
| 细胞定位 | Nucleus. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Nucleus. |
| 组织表达 | Widely expressed (Testis, Thymus, Bone marrow) |
周一至周日 8:00-18:00
