| 别名 | BFGFR; CD331; CEK; FGFBR; FLG; FLJ99988; FLT2; HBGFR; KAL2; N-SAM; OGD;FGF Receptor 1; |
| 基因名称 | FGFR1 |
| 蛋白名称 | FGFR1 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 2260 |
| Human Swissprot No. | P11362 |
| Mouse Gene ID | 14182 |
| Mouse Swissprot No. | P16092 |
| Rat Gene ID | 79114 |
| Rat Swissprot No. | Q04589 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:1000 |
| 参考分子量 | MW(Observed):140kD |
| 预测分子量 | MW(Calculated):92kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Fibroblast growth factors (FGFs) produce mitogenic and angiogenic effects in target cells by signaling through cell surface receptor tyrosine kinases. Each receptor contains an extracellular ligand binding domain, a transmembrane domain, and a cytoplasmic kinase domain. Following ligand binding and dimerization, the receptors are phosphorylated at specific tyrosine residues. Seven tyrosine residues in the cytoplasmic tail of FGFR1 can be phosphorylated: Tyr463, 583, 585, 653, 654, 730, and 766. |
| 细胞定位 | Cell membrane, Nucleus, Cytoplasm, cytosol, Cytoplasmic vesicle. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell membrane, Nucleus, Cytoplasm, cytosol, Cytoplasmic vesicle. |
| 组织表达 | Bone, Lung, Breast, Osteosarcoma, Lung squamous cell carcinoma, Breast cancer, Glioma. |
周一至周日 8:00-18:00
