| 别名 | GRK2; BARK1; FLJ16718; BETA-ARK1; ADRBK1; |
| 基因名称 | GRK2 |
| 蛋白名称 | GRK2 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 156 |
| Human Swissprot No. | P25098 |
| Mouse Swissprot No. | Q99MK8 |
| Rat Gene ID | 25238 |
| Rat Swissprot No. | P26817 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):80kD |
| 预测分子量 | MW(Calculated):80kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | GRK2 kinase activity and cellular localization are tightly regulated by interactions with activated receptors, G-beta and G-gamma subunits, adaptor proteins, phospholipids, caveolin and calmodulin, as well as by phosphorylation. PKC phosphorylation enhances GRK2 activity by promoting its membrane localization and by abolishing the inhibitory association of calmodulin. |
| 细胞定位 | Cell membrane, Cytoplasm. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell membrane, Cytoplasm. |
| 组织表达 | Widely expressed (Brain, Liver, Lung) |
周一至周日 8:00-18:00
