| 别名 | MDK;FLJ27379;MK1;NEGF2; Midkine; NEGF2; ARAP; |
| 基因名称 | Midkine |
| 蛋白名称 | Midkine |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 4192 |
| Human Swissprot No. | P21741 |
| Mouse Gene ID | 81517 |
| Mouse Swissprot No. | Q9R1S9 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):16kD |
| 预测分子量 | MW(Calculated):16kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Midkine, or MK, is a heparin-binding molecule involved in the regulation of growth and differentiation during embryogenesis. MK expression is tightly regulated during embryonic development by steroid receptors of the retinoic acid superfamily. The mature human MK protein is 118 amino acids in length and contains five intrachain disulfide bonds. MK is a non-glycosylated protein that shows greater than 87% identity between human and mouse. |
| 细胞定位 | Secreted. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Secreted. |
| 组织表达 | Kidney, Lung, Brain, Renal cell carcinoma, Lung cancer, Glioma, Breast cancer. |