| 别名 | H3.3; H3.3A; H33_HUMAN ; H3F3; Histone H3.3 ; H3 histone family 3A; H3 histone family 3B |
| 基因名称 | Histone H3.3 |
| 蛋白名称 | Histone H3.3 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 3020 |
| Human Swissprot No. | P84243 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:1000 |
| 参考分子量 | MW(Observed):15kD |
| 预测分子量 | MW(Calculated):15kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Variant histone H3 which replaces conventional H3 in a wide range of nucleosomes in active genes. Constitutes the predominant form of histone H3 in non-dividing cells and is incorporated into chromatin independently of DNA synthesis. Deposited at sites of nucleosomal displacement throughout transcribed genes, suggesting that it represents an epigenetic imprint of transcriptionally active chromatin. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. |
| 细胞定位 | Chromosome, Nucleus. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Chromosome, Nucleus. |
| 组织表达 | Widely expressed (Testis, Thymus, Bone marrow) |