| 别名 | MAP1LC3;LC3;LC3A;MAP1ALC3;MAP1BLC3 ;MAP1LC3A; |
| 基因名称 | MAP1LC3A |
| 蛋白名称 | MAP1LC3A |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 84557 |
| Human Swissprot No. | Q9H492 |
| Mouse Swissprot No. | Q91VR7 |
| Rat Swissprot No. | Q6XVN8 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):16kD |
| 预测分子量 | MW(Calculated):14kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Autophagy marker Light Chain 3 (LC3) was originally identified as a subunit of microtubule-associated proteins 1A and 1B (termed MAP1LC3), and subsequently found to contain similarity to the yeast protein Apg8/Aut7/Cvt5 critical for autophagy. Three human LC3 isoforms (LC3A, LC3B, and LC3C) undergo post-translational modifications during autophagy. Cleavage of LC3 at the carboxy terminus immediately following synthesis yields the cytosolic LC3-I form. |
| 细胞定位 | Cytoplasm, Endomembrane system, Cytoplasmic vesicle, Microtubule, Membrane. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Endomembrane system, Cytoplasmic vesicle, Microtubule, Membrane. |
| 组织表达 | Widely expressed (Liver, Kidney, Brain) |
周一至周日 8:00-18:00
