| 别名 | ASH 2; ASH2; ASH2 LIKE; ASH2 like protein; ASH2-like protein; Ash2l; ASH2L1; ASH2L2; Bre 2; Bre2; |
| 基因名称 | ASH2L |
| 蛋白名称 | ASH2L |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 9070 |
| Human Swissprot No. | Q9UBL3 |
| Mouse Gene ID | 23808 |
| Mouse Swissprot No. | Q91X20 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):69kD |
| 预测分子量 | MW(Calculated):69kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis. |
| 细胞定位 | Nucleus. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Nucleus. |
| 组织表达 | Widely expressed (Testis, Thymus, Bone marrow) |