| 别名 | ALAS1; ALAS-H; 5-aminolevulinic acid synthase 1; Delta-ALA synthase 1; ALAS3; ALASH; |
| 基因名称 | Alas1 |
| 蛋白名称 | Alas1 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 211 |
| Human Swissprot No. | P13196 |
| Mouse Gene ID | 11655 |
| Mouse Swissprot No. | Q8VC19 |
| Rat Gene ID | 65155 |
| Rat Swissprot No. | P13195 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):71kD |
| 预测分子量 | MW(Calculated):71kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | 5-aminolevulinate synthase 1 (ALAS-H) and 2 (ALAS-E) are two isoforms of ALAS, an enzyme catalyzing the first step of the heme biosynthetic pathway in mammals. The erythroid-specific isoenzyme, ALAS-E, regulates the first step of hematopoietic cell differentation and iron metabolism in the liver. ALAS-H is a housekeeping protein which mediates synthesis of early heme in the mitochondria of most cells. |
| 细胞定位 | Mitochondrion matrix |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Mitochondrion matrix |
| 组织表达 | Liver, Bone marrow, Kidney, Hepatocellular carcinoma, Leukemia, Renal cell carcinoma, Lung cancer. |
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