| 别名 | BAM; BIM; BOD; BimL; BimS; BimEL; BIM-beta6; BIM-beta7; BIM-alpha6;BCL2L11; |
| 基因名称 | Bim |
| 蛋白名称 | Bim |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 10018 |
| Human Swissprot No. | O43521 |
| Mouse Gene ID | 12125 |
| Mouse Swissprot No. | O54918 |
| Rat Gene ID | 64547 |
| Rat Swissprot No. | O88498 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:1000 |
| 参考分子量 | MW(Observed):22kD |
| 预测分子量 | MW(Calculated):22kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Bim a pro-apoptotic member of the BCL-2 protein family. Interacts with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and act as an apoptotic activator. Its expression can be induced by nerve growth factor (NGF), as well as by the forkhead transcription factor FKHR-L1, which suggests a role in neuronal and lymphocyte apoptosis. |
| 细胞定位 | Endomembrane system, Mitochondrion. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Endomembrane system, Mitochondrion. |
| 组织表达 | Widely expressed (Brain, Liver, Lung) |