| 别名 | ERBB1, Epidermal growth factor receptor precursor;Receptor protein-tyrosine kinase ErbB-1; kinase EGFR; HER1; EGFR; SA7; NISBD2; |
| 基因名称 | Phospho-EGFR (Y1068) |
| 蛋白名称 | Phospho-EGFR (Y1068) |
| 推荐应用 | |
| 反应物种 | Human Mouse |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 1956 |
| Human Swissprot No. | P00533 |
| Mouse Gene ID | 13649 |
| Mouse Swissprot No. | Q01279 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):170kD |
| 预测分子量 | MW(Calculated):134kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Receptor for epidermal growth factor (EGF) and related growth factors including TGF-alpha, amphiregulin, betacellulin, heparin-binding EGF-like growth factor, GP30 and vaccinia virus growth factor. Is involved in the control of cell growth and differentiation. . A single-pass transmembrane tyrosine kinase. Ligand binding to this receptor results in receptor dimerization, autophosphorylation (in trans), activation of various downstream signaling molecules and lysosomal degradation. Can be phosphorylated and activated by Src. |
| 细胞定位 | Cell membrane, Endoplasmic reticulum membrane, Golgi apparatus membrane, Nucleus membrane, Endosome, Nucleus, Secreted. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Phospho |
| 细胞定位 | Cell membrane, Endoplasmic reticulum membrane, Golgi apparatus membrane, Nucleus membrane, Endosome, Nucleus, Secreted. |
| 组织表达 | Epidermis, Lung, Breast, Lung adenocarcinoma, Breast cancer, Squamous cell carcinoma, Glioma. |
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