| 别名 | C-RAF, C-Raf, CRAF, EC 2.7.11.1, Protein kinase raf 1, RAF1, Raf proto-oncogene serine/threonine-protein kinase, Raf-1, kinase Raf1 |
| 基因名称 | Raf1 |
| 蛋白名称 | Raf1 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 5894 |
| Human Swissprot No. | P04049 |
| Mouse Gene ID | 110157 |
| Mouse Swissprot No. | Q99N57 |
| Rat Gene ID | 24703 |
| Rat Swissprot No. | P11345 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:1000~1:2000 |
| 参考分子量 | MW(Observed):74kD |
| 预测分子量 | MW(Calculated):73kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Raf-1 is a MAP kinase kinase kinase (MAP3K) which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated Raf-1 can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2 which in turn phosphorylate to activate the serine/threonine specific protein kinases ERK1 and ERK2. |
| 细胞定位 | Cytoplasm, Cell membrane, Mitochondrion, Nucleus. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Cell membrane, Mitochondrion, Nucleus. |
| 组织表达 | Widely expressed (Liver, Kidney, Lung) |
周一至周日 8:00-18:00
