| 别名 | CASP-1; ICE; IL-1 beta converting enzyme; IL-1BC; IL1BCE; caspase-1; |
| 基因名称 | Caspase-1 + p10 + p12 |
| 蛋白名称 | Caspase-1 + p10 + p12 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 834 |
| Human Swissprot No. | P29466 |
| Mouse Gene ID | 12362 |
| Mouse Swissprot No. | P29452 |
| Rat Swissprot No. | P43527 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):45,42,35,12,10kD |
| 预测分子量 | MW(Calculated):45kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis. |
| 细胞定位 | Cytoplasm, Cell membrane, nucleus. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Cell membrane, nucleus. |
| 组织表达 | Spleen, Liver, Lung, Macrophages, Inflammatory tissues, Lung cancer, Colon cancer. |
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