| 别名 | B7-H; B7H1; PD-L1; PDCD1L1; PDCD1LG1; PDL1; CD274; |
| 基因名称 | PD-L1 (CD274) |
| 蛋白名称 | PD-L1 (CD274) |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 29126 |
| Human Swissprot No. | Q9NZQ7 |
| Mouse Gene ID | 60533 |
| Mouse Swissprot No. | Q9EP73 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:100~1:500 |
| 参考分子量 | MW(Observed):46kD |
| 预测分子量 | MW(Calculated):33kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Programmed cell death ligand 1(CD274, or B7-H1, PD-L1), is the first member of B7 family to be discovered. B7 family molecules are type I transmembrane proteins belonging to the immunoglobulin superfamily. In concert with their CD28 family receptors, the B7s are key regulators of the adaptive immune response. CD274 is suggested a negative regulator of T and B cell, and play important role in mediating tolerance of lymphocytes to self-antigens. |
| 细胞定位 | Membrane. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Membrane. |
| 组织表达 | Placenta, Lung, Liver, Lung cancer, Melanoma, Breast cancer, Urothelial carcinoma. |
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