| 别名 | Cyclic AMP-dependent transcription factor ATF-4; CREB-2; cAMP-responsive element-binding protein 2; DNA-binding protein TAXREB67; |
| 基因名称 | ATF4 |
| 蛋白名称 | ATF4 |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 468 |
| Human Swissprot No. | P18848 |
| Mouse Gene ID | 11911 |
| Mouse Swissprot No. | Q06507 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:1000 |
| 参考分子量 | MW(Observed):50kD |
| 预测分子量 | MW(Calculated):39kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | ATF4, an activating transcription factor/cAMP-response element-binding protein family member, functions in the PERK and eIF2α ER stress responsive pathway. ER stress represses the translation of the majority of mRNAs, but selectively stimulates the translation of certain mRNAs including that of ATF-4. Induced expression of ATF-4 increases the expression of genes critical for the recovery from ER stress. |
| 细胞定位 | Nucleus, Nucleus speckle, Cytoplasm, Cell membrane, cytoskeleton, microtubule organizing center, centrosome. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Nucleus, Nucleus speckle, Cytoplasm, Cell membrane, cytoskeleton, microtubule organizing center, centrosome. |
| 组织表达 | Widely expressed (Brain, Liver, Kidney) |
周一至周日 8:00-18:00
