| 别名 | CCN E2; CCNE 2; CCNE2 protein; CYC E2; CYCE 2; CyclinE2; G1/S specific cyclin E2; |
| 基因名称 | Cyclin E2 |
| 蛋白名称 | Cyclin E2 |
| 推荐应用 | |
| 反应物种 | Human Mouse |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 9134 |
| Human Swissprot No. | O96020 |
| Mouse Gene ID | 12448 |
| Mouse Swissprot No. | Q9Z238 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:1000 |
| 参考分子量 | MW(Observed):47kD |
| 预测分子量 | MW(Calculated):47kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Cyclin E1 and cyclin E2 can associate with and activate CDK2. Upon DNA damage, upregulation/activation of the CDK inhibitors p21 Waf1/Cip1 and p27 Kip1 prevent cyclin E/CDK2 activation, resulting in G1/S arrest. Essential for the control of the cell cycle at the late G1 and early S phase. |
| 细胞定位 | Nucleus. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Nucleus. |
| 组织表达 | Testis, Thymus, Bone marrow, Lung cancer, Colon cancer, Breast cancer, Ovarian cancer. |