| 别名 | Octamer binding protein 3; Octamer binding protein 4; OCT3; OCT4; OTF3; OTF4; OTF-3; Oct-3; Oct-4; |
| 基因名称 | POU5F1 |
| 蛋白名称 | POU domain class 5 transcription factor 1 |
| 推荐应用 | |
| 反应物种 | Human Mouse |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 5460 |
| Human Swissprot No. | Q01860 |
| Mouse Gene ID | 18999 |
| Mouse Swissprot No. | P20263 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:1000 |
| 参考分子量 | MW(Observed):45kD |
| 预测分子量 | MW(Calculated):39kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Oct-4 is a transcription factor highly expressed in undifferentiated embryonic stem cells and embryonic germ cells. Forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency. |
| 细胞定位 | Cytoplasm, Nucleus. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Nucleus. |
| 组织表达 | Embryonic stem cells, Testis, Placenta, Embryonal carcinoma, Germ cell tumor, Ovarian cancer, Testicular cancer. |
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