| 别名 | Glutaminase kidney isoform; GLS; GLS1, KGA; K-glutaminase; GAM; GAC; Glutaminase C; L-glutamine amidohydrolase; |
| 基因名称 | Glutaminase |
| 蛋白名称 | Glutaminase |
| 推荐应用 | |
| 反应物种 | Human Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 2744 |
| Human Swissprot No. | O94925 |
| Mouse Gene ID | 14660 |
| Mouse Swissprot No. | D3Z7P3 |
| Rat Gene ID | 24398 |
| Rat Swissprot No. | P13264 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:1000~1:2000 |
| 参考分子量 | MW(Observed):65,73kD |
| 预测分子量 | MW(Calculated):73kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Catalyzes the first reaction in the primary pathway for the renal catabolism of glutamine. Plays a role in maintaining acid-base homeostasis. Regulates the levels of the neurotransmitter glutamate in the brain. Isoform 2 lacks catalytic activity. Isoform 1 and isoform 3 are activated by phosphate. Inhibited by BPTES. BPTES binds between subunits and favors dissociation of the tetramer into dimers. |
| 细胞定位 | Cytoplasm, Mitochondrion. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Mitochondrion. |
| 组织表达 | Brain, Liver, Kidney, Glioma, Hepatocellular carcinoma, Lung cancer, Breast cancer. |
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