| 别名 | CMH-1; ICE-LAP3; MCH3; CASP7; Caspase-7; Caspase7; |
| 基因名称 | Caspase-7 |
| 蛋白名称 | Caspase-7 |
| 推荐应用 | |
| 反应物种 | Mouse Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 840 |
| Human Swissprot No. | P97864 |
| Mouse Gene ID | 12369 |
| Mouse Swissprot No. | P97864 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:1000 |
| 参考分子量 | MW(Observed):34kD |
| 预测分子量 | MW(Calculated):34kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Caspase-7 (CMH-1, Mch3, ICE-LAP3) has been identified as a major contributor to the execution of apoptosis. Caspase-7 is an effector caspase (along with caspase-2 and -3), meaning that it cleaves essential cellular machinery rather than activating other caspases. Caspase-7 is cleaved by many enzymes, including caspases-3, -6, -8, -9 and granzyme B. Once activated, caspase-7 cleaves many of the same substrates as caspase-3, including poly (ADP-ribose) polymerase, or PARP. |
| 细胞定位 | Cytoplasm, cytosol, Nucleus, Secreted, extracellular space. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, cytosol, Nucleus, Secreted, extracellular space. |
| 组织表达 | Widely expressed (Spleen, Liver, Lung) |
周一至周日 8:00-18:00
