| 别名 | RAB5A;RAB5; RAS associated protein RAB5A; Ras related protein Rab 5A; |
| 基因名称 | Rab5 |
| 蛋白名称 | Rab5 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 5868 |
| Human Swissprot No. | P20339 |
| Mouse Gene ID | 271457 |
| Mouse Swissprot No. | Q9CQD1 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):24kD |
| 预测分子量 | MW(Calculated):24kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Rab5 is a member of the Ras superfamily of small Rab GTPases. Rab5 is localized at the plasma membrane and early endosomes and functions as a key regulator of vesicular trafficking during early endocytosis (1). The conformational change between Rab5 GTP/GDP states is essential for its biological function as a rate limiting regulator at multiple steps during endocytosis. |
| 细胞定位 | Cell membrane, Cytoplasm, Cell projection, Membrane, Endosome. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell membrane, Cytoplasm, Cell projection, Membrane, Endosome. |
| 组织表达 | Widely expressed (Liver, Kidney, Lung) |
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