| 别名 | ARRB1; ARB1; ARR1; Arrestin beta 1; Beta arrestin 1; |
| 基因名称 | ARRB1 |
| 蛋白名称 | ARRB1 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 408 |
| Human Swissprot No. | P49407 |
| Mouse Gene ID | 109689 |
| Mouse Swissprot No. | Q8BWG8 |
| Rat Gene ID | 25387 |
| Rat Swissprot No. | P29066; |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:1000 |
| 参考分子量 | MW(Observed):50kD |
| 预测分子量 | MW(Calculated):47kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | Arrestin proteins function as negative regulators of G protein-coupled receptor (GPCR) signaling. Cognate ligand binding stimulates GPCR phosphorylation, which is followed by binding of arrestin to the phosphorylated GPCR and the eventual internalization of the receptor and desensitization of GPCR signaling. Four distinct mammalian arrestin proteins are known. Arrestin 1 (also known as S-arrestin) and arrestin 4 (X-arrestin) are localized to retinal rods and cones, respectively. |
| 细胞定位 | Cell membrane, Cell projection, Coated pit, Cytoplasm, Cytoplasmic vesicle, Membrane, Nucleus. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell membrane, Cell projection, Coated pit, Cytoplasm, Cytoplasmic vesicle, Membrane, Nucleus. |
| 组织表达 | Widely expressed (Brain, Liver, Lung) |
周一至周日 8:00-18:00
