| 别名 | C-erbB-2; ErbB2; HER2, MLN 19; NEU; NEU proto-oncogene; NGL; Receptor protein-tyrosine kinase erbB-2; |
| 基因名称 | ErbB2 (HER2) |
| 蛋白名称 | ErbB2 (HER2) |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 2064 |
| Human Swissprot No. | P04626 |
| Mouse Gene ID | 13866 |
| Mouse Swissprot No. | P70424 |
| Rat Swissprot No. | P06494 |
| 特异性 | Endogenous |
| 稀释度 | WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):185kD |
| 预测分子量 | MW(Calculated):138kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | This gene encodes a member of the epidermal growth factor (EGF) receptor family of receptor tyrosine kinases. This protein has no ligand binding domain of its own and therefore cannot bind growth factors. However, it does bind tightly to other ligand-bound EGF receptor family members to form a heterodimer, stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways, such as those involving mitogen-activated protein kinase and phosphatidylinositol-3 kinase. |
| 细胞定位 | Cell membrane, Cytoplasm, Single-pass type I membrane protein. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cell membrane, Cytoplasm, Single-pass type I membrane protein. |
| 组织表达 | Breast, Ovary, Stomach, Breast cancer, Ovarian cancer, Gastric cancer, Lung cancer. |
周一至周日 8:00-18:00
