| 别名 | Bcl-2-like protein 3; Bcl-2-related protein EAT/mcl1; Bcl2-L-3; BCL2L3; EAT; Mcl-1; MCL1; mcl1/EAT; MCL1L; MCL1S; |
| 基因名称 | MCL1 |
| 蛋白名称 | MCL1 |
| 推荐应用 | |
| 反应物种 | Human,Mouse,Rat |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 4170 |
| Human Swissprot No. | Q07820 |
| Mouse Gene ID | 17210 |
| Mouse Swissprot No. | P97287 |
| Rat Gene ID | 60430 |
| Rat Swissprot No. | Q9Z1P3 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):37kDa |
| 预测分子量 | MW(Calculated):37kDa |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | MCL1 a myeloid cell leukemia protein of the Bcl-2 family of proteins. Two alternatively spliced transcripts encoding distinct isoforms have been identified. The longer gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene product (isoform 2) promotes apoptosis and is death-inducing. |
| 细胞定位 | Membrane, Cytoplasm, Mitochondrion, Nucleus. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Membrane, Cytoplasm, Mitochondrion, Nucleus. |
| 组织表达 | Ubiquitous expression |