| 别名 | CDC2; CDC28A; P34CDC2; CDK1; |
| 基因名称 | CDK1 |
| 蛋白名称 | CDK1 |
| 推荐应用 | |
| 反应物种 | Human |
| 存储缓冲液 | PBS, 50% glycerol, 0.05% Proclin 300, 0.05%BSA |
| Human Gene Link | 983 |
| Human Swissprot No. | P06493 |
| Mouse Gene ID | 12534 |
| Mouse Swissprot No. | P11440 |
| Rat Gene ID | 54237 |
| Rat Swissprot No. | P39951 |
| 特异性 | Endogenous |
| 稀释度 | IHC 1:100-1:500;WB 1:500~1:2000 |
| 参考分子量 | MW(Observed):34kD |
| 预测分子量 | MW(Calculated):34kD |
| 运输及保存条件 | -15°C to -25°C/1 year(Do not lower than -25°C) |
| 宿主 | Rabbit |
| 同种型 | IgG,Kappa |
| 背景介绍 | The cell division control protein cdc2, also known as cyclin-dependent kinase 1 (Cdk1) or p34/cdk1, plays a key role in the control of the eukaryotic cell cycle, where it is required for entry into S-phase and mitosis. Cdc2 exists as a complex with both cyclin A and cyclin B. The best characterized of these associations is the Cdc2 p34 cyclin B complex, which is required for the G2 to M phase transition. Activation of Cdc2 is controlled at several steps including cyclin binding and phosphorylation of threonine 161. |
| 细胞定位 | Cytoplasm, Mitochondrion, Nucleus, Centrosome, Cytoskeleton, Microtubule organizing center, Spindle. |
| 纯化 | Protein A |
| Clonality | Monoclonal |
| 修饰类型 | Unmodified |
| 细胞定位 | Cytoplasm, Mitochondrion, Nucleus, Centrosome, Cytoskeleton, Microtubule organizing center, Spindle. |
| 组织表达 | Testis, Thymus, Bone marrow, Lung cancer, Colon cancer, Breast cancer. |
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